Objective To establish a rapid and precise determination method for 9 herbicides (asulam, hexazinone, indaziflam, norflurazon, pyrasulfotole, pyroxasulfone, sulfosulfuron, tebuthiuron, and tepraloxydim) in dairy products that are of international concern but without established maximum residue limits (MRLs) in China.Methods The samples are ultrasonically extracted with acetonitrile-acetone mixed reagent (v∶v=8∶2), and the extract is purified by the dispersed solid-phase extraction adsorbents Florisil, N-propylethylenediamine (PSA), and anhydrous MgSO₄. A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method is established for determination.Results The nine herbicides are completely separated within 7 min. Their linear relationships are good within the range of 2.00~100 μg/L (r≥0.997). Their detection limits are 0.02~0.30 μg/kg, spiked recoveries are 71.6%~104.1%, and relative standard deviations are 0.4%~10.3%.Conclusion This method is simple to operate, has high sensitivity and good reproducibility, and can be used for rapid determination of residues of the 9 herbicides in dairy products.