Research progress on the mechanism of food-derived antihypertensive peptides

doi:10.13652/j.spjx.1003.5788.2023.80842

Home > Archive>Volume 40, Issue 3, 2024 >217-224. DOI:10.13652/j.spjx.1003.5788.2023.80842

Research progress on the mechanism of food-derived antihypertensive peptides
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                        10.13652/j.spjx.1003.5788.2023.80842
                    
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Affiliation:(1. Fujian Province Key Laboratory for the Development of Bioactive Material from Marine Algae, College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou, Fujian 362000, China; 2. Key Laboratory of Inshore Resources and Biotechnology Fujian Province University, Quanzhou, Fujian 362000, China; 3. College of Food Science, Fujian Agriculture University, Fuzhou, Fujian 350002, China)
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Abstract:

In this review, several mechanisms of antihypertensive peptides derived from food and its by-products were summarized. Mechanisms based on the RAAS system such as ACE/Ang Ⅱ/AT1R signaling pathways and ACE2/Ang (1-7)/MasR signaling pathways were included. Mechanisms targeting at KNOS system including PI3K/Akt/eNOS signaling pathway, PPAR-γ/caspase3/MAPK/eNOS signaling pathway and L-type Ca²⁺ channel were also discussed. In addition, the pathways of reducing blood pressure by inhibiting endothelin-converting enzyme (ECE) activity discovered in recent years were also introduced.

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王宝贝,张慧,刘宇松,等.食源性多肽的降血压作用及其机制研究进展[J].食品与机械英文版,2024,40(3):217-224.

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Received:August 30,2023
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Online: April 30,2024
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