Objective: To understand the current situation and level of mercury pollution in main aquatic products in Maoming area, so as to provide the basis for quality supervision and safe consumption of aquatic products. Methods: Ten kinds of aquatic products commonly consumed by residents in four districts of Maoming were selected as the evaluation objects according to the questionnaire. The total mercury content of the samples was determined by atomic fluorescence Spectrophotometer, pollution degree assessment, dietary exposure assessment and health risk assessment were carried out by single factor pollution index method, weekly average exposure per unit weight and target hazard quotient respectively. Results: The results showed that 42.95% of the residents were not aware of the harm of mercury pollution in aquatic products, and the total mercury content in 10 kinds of aquatic products ranged from ND～0.141 8 mg/kg, the detection rate was 35.9% The total mercury pollution index （P_i） of 38 out of 39 samples was less than 0.2, and the weekly average exposure per unit weight of total mercury was 0.090 9 μg/（kg·BW）, which accounted for 2.273% of Provisional Tolerable Weekly Intake （PTWI）. The target hazard quotient of total mercury in aquatic products was less than 1, and the average target risk factor was 0.13. Conclusion: Overall, the total mercury content of 10 aquatic products in the Maoming region did not exceed the national limits, and the level of mercury pollution is at a safe level, the potential health risks are low and safe to eat.