The review describes the paralytic shellfish toxins (Paralytic Shellfish Toxins, PSTs) produced by harmful toxic algae. Species specificity of PSTs toxin accumulation content. The related research on paralytic shellfish toxins is reviewed from the accumulation, transformation, metabolism and purification of PSTs, and it is pointed out that efficient detoxification of aquatic products by means of optimization or combination of transient purification, biosorption, microbial metabolism and other purification methods is the future research direction.