Anti-oxidation is an effective process to inhibit the oxidation of free radicals. The human body produces anti-oxidation substances as well as free radicals. With the improvement of material life, people hope to satisfy their health needs by eating natural and healthy food. In this paper, through the analysis of the raw materials and the compatibility of the products, it is found that the food and the extract are widely used in the anti-oxidation functional food, and the anti-oxidation function of the raw materials and the anti-oxidation function of the dietary supplement have been developed, the general situation of the use of food and its extract in all functional foods was summarized. Finally, some suggestions were put forward for the choice of food and its extract.