The spoilage of aquatic products is mainly caused by microbial activities. In this paper, the Specific Spoilage Organisms (SSO) in aquatic products, Quorum Sensing (QS) signal of microbial molecules, the resource and function methods of QS inhibitors were described, respectively. The existing problems and solutions of current QS inhibitors from plant were proposed as well so as to provide the theoretical reference for the research of preservatives for controlling the QS in aquatic products.