Lactic acid bacteria with probiotic function were isolated and screened from the intestinal track of longevity crowd in Kashi, Xinjiang, and their ability to triglyceride-reducing in vitro were investigated. The results showed that the fourteen of forty-one strains of lactic acid bacteria with high triglyceride-reducing rates, were higher than 15%. Among them, strain A2-1, A1-2, A3-1, A4-6 and A4-1 with higher survival rates s in artificial gastric juice at pH 3.0 were 63.22%，60.01%，58.94%，56.14%，50.29%, respectively. Moreover, the survival rates of these 5 strains in MRS broth with 1, 3 and 5 g/L bile salt were also relatively high, and the survival rates of A1-2 were the highest, which were 46.61%, 42.65%, 16.32%, respectively. The 5 strains of lactic acid bacteria had strong properties of acid resistant, bile-salt-tolerant and depredating the triglyceride acid resistant and were biochemical identifying the 16S rDNA. Finally, A1-2 and A4-1were confirmed to be Lactobacillus plantarum andLactobacillus paracasei respectively. A2-1, A3-1 and, A4-6 were identified to be Enterococcus faecium.