Objective To prepare metal complexes of biochanin A (BA) and explore their biological activities.Methods Biochanin A was used as the ligand to design and synthesize biochanin A-copper (BA-Cu), biochanin A-zinc (BA-Zn), and biochanin A-chromium (BA-Cr) metal complexes. The structures of the complexes were characterized using methods such as ultraviolet spectroscopy and infrared spectroscopy. The antioxidant activities of the three biochanin A metal complexes were evaluated using the phosphomolybdate complex method, and their anticancer activities were assessed using the CCK-8 assay.Results The experiments successfully prepared the three biochanin A metal complexes, i.e., BA-Cu, BA-Zn, and BA-Cr. All three metal complexes exhibited good antioxidant activities, which were higher than those of the ligand biochanin A and the positive control drug BHT. Among them, BA-Cr exhibited the best antioxidant activity. The three biochanin A metal complexes inhibited the proliferation of human lung cancer A549 cells, cervical cancer Hela cells, and breast cancer MCF-7 cells, with overall inhibitory effects greater than those of the ligand biochanin A. Among them, BA-Zn demonstrated the best anticancer activity.Conclusion The three biochanin A metal complexes, BA-Cu, BA-Zn, and BA-Cr, were successfully prepared. Among them, BA-Cr exhibited the best antioxidant activity, while BA-Zn demonstrated the best anticancer activity.