The technical characteristics of various fluorine content detection methods in recent years are summarized, with three dimensions focused on, namely, detection principle, technical characteristics, and application status, to comprehensively describe domestic and international indirect detection techniques of total fluorine content in food packaging materials. The existing detection methods are sorted out according to the two links of sample pre-treatment and fluorine content determination, and the technical parameters and application scenarios are compared. In addition, key parameters of fluorine content detection techniques are analyzed and evaluated, such as accuracy, precision, stability, detection time, and cost-effectiveness. Suggestions are put forward for further improvement and optimization of the techniques.