The quality of food safety sampling inspection data are a comprehensive reflection of the technical ability, professional competence, and management service level of inspection institutions. It is an important guarantee for the effectiveness of food safety sampling inspection work, and a key factor in doing a good job in verification and disposal work. Market regulatory administrations have strengthened the verification of food sampling inspection data in recent years, which have played a good role in improving the quality of food safety sampling inspection data. However, it was found that some inspection and testing institutions have some problems in sampling, inspection, and report standardization during the data verification process. It will have a certain impact on subsequent regulatory and administrative penalties. This article analyzes common problems in the daily sampling inspection process and proposes some measures to optimize food safety sampling inspection work, wishing to provide reference for food safety supervision and sampling inspection personnel.