Objective: This study aimed to provide a rapid and efficient pretreatment method to detect the mineral elements in infant formula milk powder. Methods: Low-temperature rapid wet digestion (digesting temperature was 120 ℃ and digesting time was 90 min) combined with the inductively coupled plasma optical emission spectroscopy (ICP-OES) was used to determine the concentrations of K, Na, Ca, Mg, P, Fe, Zn, Cu, and Mn in infant formula milk powder. Results: The linear correlation coefficients of standard curves for these nine elements were all over 0.999 9. This method was verified by the reference materials in infant formula milk powder, and the detection values of each element were all within the range of their characteristic values. Besides, the spiked recovery rate of elements in a commercial infant milk powder was verified. Its recovery rate was 95.0%~102.0% and the relative standard deviation was within 5%. Conclusion: This method was fast and efficient, which is suitable for the digestion of mineral elements in infant formula milk powder.