Applied the existing adaptive grid technology to the counter-rotating twin-screw extruder, useed Autocad software to draw the end profile of the counter-rotating thread element, and establisheed the corresponding 3D model on the Solidworks software. Then imported the geometric model Gambit software for mesh generation. Selecting the adaptable mesh technology of Polyflow software, the mesh of the fluid channel is locally densified according to the Maxdiv value. The finite element solution task of isothermal transient flow problem of counter-rotating twin-screw was designed, and the Maxdiv value was also studied. The effects of the value were studied, on the shear rate field, viscosity field, and pressure field of the flow channel. And compared the effects of the number of mesh refinements in the adaptive grid technology on the computing resources. It is showed that Application potential of the method in the twin-screw extrusion process during the simulation.