To provide a basis of quality control and safety evalua-tion for developing medicine and functional food of Inonotus obliquus, 4 kinds of heavy metals including lead, cadmium, mercury, arsenic and 18 kinds of microelements including aluminum, boron, barium, calcium, tin, cobalt, copper, iron, potassium, magnesium, manganese, sodium, nickel, phosphorus, strontium, titanium, vanadium, zinc in different color, different part, and different products were detected by national standard, and relative statistical analyses were also carried out. Results showed that the contents of 22 inorganic elements in crude I. obliquus products were higher than that in refined I. obliquus products, while the contents of micronutrient in dark I. obliquus were higher than the light one especially in aluminum, barium, tin, iron, magnesium, titanium, and vanadium. The contents of micronutrient in inside of I. obliquus were higher than that in coat especially in aluminum, calcium, copper, iron, sodium, and phosphorus. The contents of heavy metals in raw materials and deep processing products of I. obliquus from Russia origin were within the scope of the national standards. The microelement was different depending on different materials. It ensures the efficiency for development of I. obliquus.