In view of the reduction of food quality due to the destructs cellular structure by the large ice crystals in quick-freezing preservation process, regarding cell solution as water and solute in binary system, the five-fold symmetric phase-field model with anisotropy of strong interface energy was used to reproducing the evolution process of ice crystal growth, the effect of freezing times on the behavior of ice crystal growth was studied. The results showed that simulation result of ice crystal growth were consistent with the actual morphology, both of which had developed side-branching in the middle of the main branch, the root of the main branch was necked, and the corners were formed at the tips of them. The diffusion channel between the main branch and the side-branch was not smooth, and the solute concentration in the semi-enclosed liquid phase reached 1.76%, the growth of ice crystals was inhibited. The dimensionless temperature of solid liquid interface in the root of the ice crystal main branch changed gently, but changed sharply in the tip. As the freezing time increased, the dimensionless temperature and solute concentration first rapid increased then gradually became stable, and the tip growth rate and curvature radius sharply decreased and then gradually became stable. The ice crystal changed from the initial approximate pentagonal structure through the 5 main stem structure to the five-fold symmetric multi-branch faceted structure.