On the basis of the analysis of fish transportation stress, the blood biochemical indexes, non specific immune cells and antioxidative functions were integrated, and the stress in the transportation of fish was reviewed in detail from different stress angles, such as hypoxia stress, ammonia nitrogen stress, density stress, objective transportation condition stress, temperature stress and so on. The reaction inducing factors and effects in the process of fish live transportation were proposed, in order to provide reference for the circulation and sale of live fish.