To investigate the effect of hypobaric storage on the fresh-keeping of Agaricus bisporus, The results showed that the low pressure-treated groups (25.3 kPa and 50.7 kPa) were able to maintain the good sensory quality of white button mushrooms, decrease respiration of mushrooms, significantly delay the change of the mushroom whiteness and hardness (P<0.05), maintain a high soluble solids (P<0.05), inhibit the PPO activity (P<0.05). Nevertheless, the hypobaric treatment increased weight loss of mushroom (P<0.05) and the lower pressure brought the higher the rate of weight loss. However, the weight loss of 50.7 kPa and 76.0 kPa group was at an acceptable range. Above all, the 50.7 kPa group achieved the best effects.