Gelatin, the hydrolyzed biopolymer of collagen, is widely used in pharmaceutical, food industries etc. However, its inherent physical and chemical properties can not meet production needs (especially fish gelatin). The research of gelatin modification attracts more attentions. Gelatin chemical crosslinking modified with inorganic compounds (MgSO₄, CaCl₂ and NaCl), organic compounds (pectin, chitosan and aldehyde) and Transglutaminase was introduced in this paper.