High pressure sterilization equipment’s strict sealing requires the synchronization system which push plug’s movement must have high synchronization accuracy. However, because of the dynamic load, friction, oil leakage, the plugeasily prone to deflection, which are greatly affecting the sealing performance. Considering about this problem, the synchronous system’s mathematical model was established. And then, the control method was also proposed: a PID control was using to the horizontal motion. And the fuzzy PID was used to control the deflection movement. The simulation results show that: the plug under this control strategy not only has a high precision horizontal motion, but also has a strong restore balance ability. All of these provide a reliable reference to improve the effect of sterilization equipment.